目的 調(diào)查分析氟比洛芬酯注射液的臨床應(yīng)用情況并進(jìn)行合理用藥評(píng)價(jià)。方法 從醫(yī)院管理系統(tǒng)中抽取2019年1月1日—2020年12月31日天津市寶坻區(qū)人民醫(yī)院應(yīng)用氟比洛芬酯注射液的住院患者臨床資料和用藥的基本情況資料。選擇氟比洛芬酯注射液用量排名前5位的科室，每個(gè)科室隨機(jī)抽取40例患者，對(duì)抽取調(diào)查的200例患者氟比洛芬酯注射液的適應(yīng)癥、用法用量等進(jìn)行用藥合理性評(píng)價(jià)。結(jié)果 2019年1月1日—2020年12月31日住院患者應(yīng)用氟比洛芬酯注射液共2 970例，其中男性1 683例，女性1 287例；骨科等開展手術(shù)的外科科室使用量較多（33.87%）；抽取的200例患者中，5例（2.5%）為超適應(yīng)癥用藥，3例（1.5%）為聯(lián)合用藥不適宜，2例（1.0%）為用藥選擇不適宜，9例（4.5%）為用藥療程不適宜，4例（2.0%）患者年齡大于60歲患者使用日劑量為200 mg。結(jié)論 醫(yī)院應(yīng)當(dāng)進(jìn)一步采取科學(xué)管理策略，加強(qiáng)氟比洛芬酯注射液臨床使用管理。

Objective To investigate and analyze the clinical application of Flurbiprofen Axetil Injection and evaluate its rational use. Methods The clinical data and medication information of inpatients receiving Flurbiprofen Axetil Injection in Baodi Hospital from January 1, 2019 to December 31, 2020 were extracted from the hospital management system. The top 5 departments of Flurbiprofen Axetil Injection dosage were selected, 40 patients were randomly selected from each department, and the indications, usage and dosage of flurbiprofen ester injection in 200 patients were evaluated for rationality of drug use. Results From January 1, 2019 to December 31, 2020, a total of 2 970 hospitalized patients received Flurbiprofen Axetil Injection, including 1 683 males and 1 287 females. Orthopedics and other surgical departments used more (33.87%). Among the 200 patients selected, 5 (2.5%) were off-label, 3 (1.5%) were unsuitable combination, 2 (1.0%) were unsuitable choice of medication, 9 (4.5%) were unsuitable course of medication, and 4 (2.0%) were older than 60 years and received a daily dose of 200 mg. Conclusion Hospitals should further adopt scientific management strategies to strengthen clinical management of Flurbiprofen Ester Injection.

R969.3