目的 分析解放軍總醫(yī)院第一醫(yī)學(xué)中心門診抗血栓藥物使用情況，分析用藥特點，指導(dǎo)合理用藥。方法 采用世界衛(wèi)生組織推薦限定日劑量法，對醫(yī)院門診抗血栓藥物銷售金額、用藥頻度（DDDs）、日均費用（DDC）以及金額排序與用藥頻度排序比值（B/A）進行回顧性分析。結(jié)果 抗血小板藥物銷售金額和DDDs排序靠前，抗凝藥物居中，溶栓藥物使用頻率最低。舒洛地特、貝前列素鈉、達比加群酯、蚓激酶、替格瑞洛和依諾肝素鈉DDDs呈增長趨勢，阿司匹林、華法林、前列地爾和雙嘧達莫呈下降趨勢。DDC值為0.69～10 721.16元，區(qū)間大，且多數(shù)品種DDC在2017—2018年略有下降，2018—2019年比較穩(wěn)定。傳統(tǒng)藥物如阿司匹林、華法林、肝素鈉等B/A均≥1.00，其他均<1.00。結(jié)論 醫(yī)院門診抗血栓藥應(yīng)用情況基本合理，但對個別金額增長較快的藥品，需密切關(guān)注。

Objective To analyze the use of antithrombotic drugs in The First Medical Center of PLA General Hospital, and analyze the characteristics of drug use, and guide rational drug use. Methods The consumption sum, DDDs, DDC, and B/A of antithrombotic drugs in outpatient department of The First Medical Center of PLA General Hospital from 2017 to 2019 were retrospectively analyzed by using who recommended limited daily dose method. Results The consumption sum and DDDs of antiplatelet drugs ranked first, anticoagulants ranked middle, and the use frequency of thrombolytic drugs was the lowest. The DDDs of sulodexide, beprost sodium, dabigatran, lumbrokinase, ticagrelor, and enoxaparin sodium were increased, while aspirin, warfarin, alprostadil, and dipyridamole were decreased. The DDC value was 0.69 to 10 721.16, and the DDC of most varieties were decreased slightly from 2017 to 2018, but remained stable from 2018 to 2019. B/A of traditional drugs, such as aspirin, warfarin and heparin sodium, were all ≥ 1.00, while others were all < 1.00. Conclusion The application of antithrombotic drugs in outpatients of The First Medical Center of PLA General Hospital is basically reasonable, but attention should be paid to some drugs with rapid increase in amount.

R971