目的 分析國家藥品集中采購對天津市北辰醫(yī)院門診降壓藥使用情況的影響。方法 提取國家藥品集中采購政策實施前后門診降壓藥的用藥數(shù)據，采用藥物經濟學方法回顧性分析藥品價格、數(shù)量、金額、用藥頻度（DDDs）、日均費用（DDC）和換藥率等變化情況。結果 2018—2022年天津市北辰醫(yī)院門診降壓藥共涉及9個品種，集采藥較原用藥相比，降價幅度均在50%以上，銷售金額減少132.48萬元，同比降低54.26%，DDDs同比升高29.01%，DDC均有不同程度的降低。70.71%～100.00%患者將非集采藥更換成集采藥使用。結論 國家藥品集中采購政策切實降低了天津市北辰醫(yī)院高血壓患者用藥負擔，提高了醫(yī)保資金使用效率，同時醫(yī)生和患者越來越傾向于使用集采藥，集采藥逐步得到大眾認可。

Objective To analyze the influence of national centralized drug procurement on the use of antihypertensive drugs in outpatient department of Tianjin Beichen Hospital. Methods The data of antihypertensive drugs used in outpatients before and after the implementation of national centralized drug procurement policy were extracted, and the changes of drug price, quantity, amount, DDDs, DDC and dressing change rate were analyzed retrospectively by pharmacoeconomics method. Results From 2018 to 2022, 9 varieties of antihypertensive drugs were involved in the outpatient department of Tianjin Beichen Hospital. Compared with the original drugs, the price reduction of collected drugs was more than 50%, the consumption sum decreased by 1324800 yuan, 54.26% lower than that of the previous year, DDDs increased by 29.01%, and DDC decreased to varying degrees. 70.71%-100.00% of patients changed the uncollected medicine into the collected medicine. Conclusion The national policy of centralized drug procurement has effectively reduced the burden of medication for hypertension patients and improved the efficiency of medical insurance funds. At the same time, doctors and patients are more and more inclined to use collection medicine, and collection medicine is gradually recognized by the public.

R286.2

天津市北辰區(qū)衛(wèi)健系統(tǒng)科技項目（SHGY-2020033）