尿囊素是一種天然的、安全的，無(wú)毒的咪唑類(lèi)雜環(huán)化合物，具有多種藥理作用。隨著尿囊素藥理特性的不斷深入研究，發(fā)現(xiàn)其涉及到多種分子機(jī)制，如激活咪唑啉受體、提高能量代謝、抗氧化應(yīng)激、抗炎等。歸納總結(jié)了尿囊素的藥理作用機(jī)制，以期為尿囊素的后續(xù)研究和開(kāi)發(fā)利用提供參考。

Allantoin is a natural, safe, non-toxic imidazole heterocyclic compound, which has a variety of pharmacological effects. With the further study of the pharmacological properties of allantoin, it involves a variety of molecular mechanisms, such as activation of imidazoline receptors, improvement of energy metabolism, antioxidant stress, anti-inflammatory, etc. Therefore, this paper summarized the mechanism of allantoin, so as to provide a reference for the follow-up research and development of allantoin.

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國(guó)家自然科學(xué)基金青年科學(xué)基金資助項(xiàng)目（82000842）；廣東省基礎(chǔ)與應(yīng)用基礎(chǔ)研究基金資助項(xiàng)目（2021A1515010151）