淫羊藿苷是淫羊藿中主要活性成分，具有抗腫瘤、抗炎、增強免疫、抗肝毒性、抗氧化等多種藥理活性。淫羊藿苷可通過多靶點、多途徑對中樞神經(jīng)系統(tǒng)疾病產(chǎn)生保護作用，如淫羊藿苷具有抗抑郁作用，對阿爾茨海默病、帕金森病、缺血性腦卒中、多發(fā)性硬化具有保護作用。為了進一步擴大淫羊藿苷在臨床治療中的應用，綜述了淫羊藿苷改善中樞神經(jīng)系統(tǒng)疾病及其作用機制。

Icariin is one of main active components in Epimedii Folium, which has various pharmacological activities, such as anti- tumor, anti-inflammatory, immune enhancement, anti-hepatotoxicity, antioxidant, etc. Icariin can protect central nervous system diseases through multiple targets and pathways. Icariin has antidepressant effects and protective effects on Alzheimer's disease, Parkinson's disease, ischemic stroke, and multiple sclerosis. In order to further expand the application of icariin in clinical application, this article reviews the improvement of central nervous system diseases by icariin and its mechanism.

R971

國家自然科學基金資助項目（31872175）；咸陽師范學院科研計劃面上項目（XSYK22002）