綠茶中的活性成分已經(jīng)被證明具有預(yù)防和控制癌癥的作用，其中表沒(méi)食子兒茶素沒(méi)食子酸酯（EGCG）抗癌活性最高。EGCG能夠通過(guò)調(diào)控氧化應(yīng)激、阻滯腫瘤細(xì)胞周期、抑制腫瘤血管形成、誘導(dǎo)腫瘤細(xì)胞凋亡等途徑實(shí)現(xiàn)抗腫瘤效果。因此對(duì)EGCG抗腫瘤作用機(jī)制的進(jìn)行了綜述，以期為EGCG的臨床應(yīng)用提供參考。

The active ingredients in green tea have been proved to have anticancer effects, and (-)-epigallocatechin gallate (EGCG) had the highest anticancer activity. EGCG could achieve anticancer effects by regulating oxidative stress, blocking tumor cell cycle, inhibiting tumor angiogenesis, and inducing cancer cell apoptosis. This article reviews the mechanism of anticancer action of EGCG in order to provide reference for its clinical application.

R979.1

省部共建食品營(yíng)養(yǎng)與安全國(guó)家重點(diǎn)實(shí)驗(yàn)室開(kāi)放課題（20210829）