目的 建立基于加權(quán)TOPSIS法的兒童患者注射用炎琥寧的藥物利用評價(jià)，促進(jìn)其臨床合理應(yīng)用。方法 以注射用炎琥寧藥品說明書為依據(jù)，參考注射用炎琥寧臨床使用相關(guān)文獻(xiàn)，建立基于加權(quán)TOPSIS法的兒童患者注射用炎琥寧的藥物利用評價(jià)標(biāo)準(zhǔn)，依據(jù)建立的評價(jià)標(biāo)準(zhǔn)回顧性評價(jià)徐州醫(yī)科大學(xué)附屬徐州兒童醫(yī)院2022年1月-2022年12月注射用炎琥寧使用情況。結(jié)果 360份評價(jià)病歷加權(quán)TOPSIS法評價(jià)顯示，與最優(yōu)方案最高接近度為84.06%，最低接近度為40.03%。相對接近度<60%的有165例（45.83%），60%≤相對接近度<70%的有159例（44.17%），70%≤相對接近度<80%的有32例（8.89%），80%≤相對接近度<90%的有4例（1.11%），沒有相對接近度≥ 90%的病歷。結(jié)論 基于加權(quán)TOPSIS法的兒童患者注射用炎琥寧藥物利用評價(jià)標(biāo)準(zhǔn)可以用于該藥在兒童患者的用藥合理性評價(jià)，評價(jià)結(jié)果顯示徐州醫(yī)科大學(xué)附屬徐州兒童醫(yī)院注射用炎琥寧臨床應(yīng)用中存在不合理用藥情況，需進(jìn)一步加強(qiáng)管控。

Objective To establish weighted TOPSIS method for evaluating Potassium Sodium Dehydroandroandrographolide Succinate for injection and promote its rational clinical application. Methods The evaluation criteria of Potassium Sodium Dehydroandroandrographolide Succinate for injection in children was established with reference to its package insert and the relevant guidelines. The use of Potassium Sodium Dehydroandroandrographolide Succinate for injection in in Xuzhou Children's Hospital, Xuzhou Medical University from January 2022 to December 2022 were retrospectively evaluated according to the established evaluation criteria. Results The evaluation of 360 medical records by weighted TOPSIS method showed that the highest approximation to the optimal scheme was 84.06%, and the lowest approximation was 40.03%. There were 165 cases (45.83%) in relative proximity < 60%, 159 cases (44.17%) in relative proximity between 60% to 70%, 32 cases (8.89%) in relative proximity between 70% to 80%, 4 cases (1.11%) in relative proximity between 80% to 90%, and no case in relative proximity > 90%. Conclusion The evaluation criteria of Potassium Sodium Dehydroandroandrographolide Succinate for injection in children based on the weighted TOPSIS method can be used to evaluate the rationality of Potassium Sodium Dehydroandroandrographolide Succinate for injection in children. The evaluation results show that there are still unreasonable use of Potassium Sodium Dehydroandroandrographolide Succinate for injection in Xuzhou Children's Hospital, Xuzhou Medical University, which needs to be further strengthened.

R978.7

徐州市兒童醫(yī)院科研項(xiàng)目（22040426）