高熱環(huán)境下水、電解質(zhì)流失嚴重，機體散熱功能下降，可引起一系列熱應激產(chǎn)生的損傷性疾病，嚴重威脅著急性進入和需長期在高熱環(huán)境中工作的人員的身心健康和工作能力。姜黃素是親脂類多酚化合物，是姜黃中的主要有效成分，具有廣泛的藥理作用。姜黃素在高熱環(huán)境下對各類器官發(fā)揮保護作用，如心血管、肺和氣道、骨骼肌、肝臟、腎臟、胃腸道等?？偨Y了在高熱環(huán)境下姜黃素對器官的保護作用，為姜黃素防治熱應激產(chǎn)生的損傷性疾病提供參考。

Objective: The loss of water and electrolyte in high temperature environment is serious, and the heat dissipation function of the body reduces, which can cause a series of damage diseases caused by heat stress, and it seriously threatens the physical and mental health and work ability of personnel who have acute entry and need to work in high heat environments for a long time. Curcumin is a lipophilic polyphenolic compound, which is the main active ingredient extracted from Curcumae Longae Rhizoma, and has a wide range of pharmacological effects. Curcumin could play a protective role in organs in a high fever environment, such as cardiovascular, lung and airway, skeletal muscle, liver, kidney, and gastrointestinal tract, etc. This paper summarizes the protective effect of curcumin on organs in high heat environments, so as to provide reference for the prevention and treatment of heat stress-induced injury diseases with curcumin.

R285.5；R977

四川省自然科學基金資助項目（2022NSFSC1422）；四川省中醫(yī)藥管理局科學技術研究專項課題（2021MS536）；四川省中醫(yī)藥管理局科學技術研究專項課題（2021MS422）