青光眼是一種神經(jīng)退行性疾病，是全球范圍內(nèi)導致失明的主要原因。早期診斷和正確治療對于防治青光眼、預防視力障礙非常重要。白藜蘆醇是一種天然成分，具有多種活性，可通過降低眼壓，降低炎癥反應，降低氧化應激反應，阻止細胞凋亡，促進視神經(jīng)修復，改善線粒體生物合成對青光眼視網(wǎng)膜損傷發(fā)揮保護作用?？偨Y(jié)了白藜蘆醇防治青光眼的藥理作用研究進展，分析其降低視網(wǎng)膜損傷的作用機制，為白藜蘆醇的臨床應用提供支持。

Glaucoma is a neurodegenerative disease and the leading cause of blindness worldwide. Early diagnosis and proper treatment are crucial for the prevention and treatment of glaucoma and visual impairment. Resveratrol is a natural ingredient with multiple activities. Resveratrol can protect against glaucoma and retinal damage by reducing intraocular pressure, reducing inflammation, reducing oxidative stress, preventing cell apoptosis, promoting optic nerve repair, and improving mitochondrial biosynthesis. This article summarizes the research progress of resveratrol in prevention and treatment of glaucoma, analyzes its mechanism of reducing retinal damage, and provides support for the clinical application of resveratrol.

R988.1

河北省重點研發(fā)計劃項目（213777108D）