2型糖尿病患者血糖波動增加了飲食管理的難度。治療2型糖尿病的常見藥物胰高血糖素樣肽-1（GLP-1）受體激動劑、二肽基肽酶-4（DPP-4）抑制劑、二甲雙胍類藥物、α-葡萄糖苷酶抑制劑、鈉-葡萄糖共轉(zhuǎn)運(yùn)蛋白2（SGLT-2）抑制劑、噻唑烷二酮類藥物可以通過多種路徑影響食欲。探討了各類2型糖尿病治療藥物影響食欲的研究進(jìn)展，為2型糖尿病治療藥物的臨床應(yīng)用提供了參考。

The fluctuation of blood sugar in type 2 diabetes patients increases the difficulty of diet management. Glucagon-like peptide-1 (GLP-1) receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, metformin, α-glucosidase inhibitors, sodium glucose cotransporter protein 2 (SGLT-2) inhibitors, and thiazolidinedione can affect appetite through multiple paths. This article discusses the research progress of various types of therapeutic drugs for type 2 diabetes affecting appetite, and provided a reference for the clinical application of therapeutic drugs for type 2 diabetes.

R977

國家自然科學(xué)基金面上項(xiàng)目（82274486）；四川省中醫(yī)藥管理局項(xiàng)目（2023zd011）