[關(guān)鍵詞]
[摘要]
乳腺癌為女性常見惡性腫瘤之一,是導(dǎo)致女性癌癥死亡的第2大惡性腫瘤,發(fā)病人群逐漸增多且呈年輕化趨勢(shì)。乳腺癌的傳統(tǒng)放化療存在嚴(yán)重不良反應(yīng),限制了長(zhǎng)期使用。黃芩素是由黃芩干燥根中提取的天然黃酮類成分,可通過抑制細(xì)胞增殖、阻滯腫瘤細(xì)胞侵襲和轉(zhuǎn)移、促進(jìn)細(xì)胞凋亡、逆轉(zhuǎn)細(xì)胞耐藥性發(fā)揮抗乳腺癌的作用??偨Y(jié)了黃芩素抗乳腺癌的研究進(jìn)展,希望為乳腺癌的藥物治療提供參考。
[Key word]
[Abstract]
Breast cancer is one of the common malignant tumors in women and the second leading cause of cancer death in women. The incidence is gradually increasing and is showing a trend of younger age. Traditional radiotherapy and chemotherapy for breast cancer have serious adverse reactions, which limit long-term use. Baicalin is a natural flavonoid component extracted from dried roots of Scutellariae Radix. Baicalein can play an anti-breast cancer role by inhibiting cell proliferation, limiting tumor cell invasion and metastasis, promoting cell apoptosis, and reversing cell resistance. This article summarizes the research progress of baicalein against breast cancer, hoping to provide a reference for drug therapy of breast cancer.
[中圖分類號(hào)]
R979.1
[基金項(xiàng)目]