白藜蘆醇是一種二苯乙烯類化合物，主要來源于葡萄、花生、藍(lán)莓等植物，在抗腫瘤方面展現(xiàn)出巨大潛力，不僅能夠抑制腫瘤細(xì)胞增殖，誘導(dǎo)腫瘤細(xì)胞凋亡，還能抑制腫瘤侵襲與轉(zhuǎn)移、抑制外泌體分泌、增強(qiáng)放化療敏感性、調(diào)節(jié)腫瘤微環(huán)境發(fā)揮抗腫瘤作用。綜述了白藜蘆醇抗腫瘤作用的研究進(jìn)展，探討其在腫瘤治療中的應(yīng)用潛力。

Resveratrol is a stilbene compound mainly derived from plants such as grapes, peanuts, blueberries, etc. Resveratrol has shown great potential in anti-tumor activities. Resveratrol not only inhibits tumor cell proliferation and induces tumor cell apoptosis, but also inhibits tumor invasion and metastasis, suppresses exosome secretion, enhances chemoradiotherapy sensitivity, and regulates the tumor microenvironment to exert anti-tumor effects. This article reviews the research progress on the anti-tumor effects of resveratrol and explores its potential applications in tumor treatment.

R965

國家自然科學(xué)基金青年科學(xué)基金資助項(xiàng)目（81402344）；陜西省自然科學(xué)基礎(chǔ)研究計(jì)劃面上項(xiàng)目（2023JC-YB-745）；秦創(chuàng)原中醫(yī)藥產(chǎn)業(yè)創(chuàng)新聚集區(qū)項(xiàng)目（L2024-QCY-ZYYJJQ-X143）