電離輻射超過一定劑量時，可使幾乎所有器官、系統(tǒng)均發(fā)生病理改變。電離輻射后產(chǎn)生的大量炎性因子和趨化因子也會參與皮膚、肺和大腦的反應(yīng)，導(dǎo)致放射性皮炎、放射性肺、腦損傷等。因此需要開發(fā)能夠有針對性的防治電離輻射的藥物?？闺婋x輻射藥物包括恢復(fù)造血功能藥物、抗氧化劑、抗炎藥和天然抗輻射藥。總結(jié)了抗電離輻射藥物的研究進(jìn)展，希望為抗電離輻射藥物的選擇和研發(fā)提供參考。

When ionizing radiation exceeds a certain dose, it can cause pathological changes in almost all organs and systems. The large amount of inflammatory and chemokines produced after ionizing radiation can also participate in the reactions of the skin, lungs, and brain, leading to radiation dermatitis, radiation lung, brain damage, and so on. Therefore, it is necessary to develop targeted drugs for the prevention and treatment of ionizing radiation. Anti-ionizing radiation drugs include drugs for restoring hematopoietic function, antioxidants, anti-inflammatory drugs, and natural anti-radiation drugs. This article summarizes the research progress of anti-ionizing radiation drugs, hoping to provide reference for the selection and development of anti-ionizing radiation drugs.

R979.61