心血管疾病是全球范圍內(nèi)致死、殘疾的主要原因之一，口服抗血小板藥物在預防和治療心血管疾病方面發(fā)揮不可替代的作用。口服抗血小板藥物臨床應用面臨出血風險、藥物抵抗、個體差異、長期治療的依從性的挑戰(zhàn)，需要制定應對挑戰(zhàn)的策略?？偨Y(jié)了常見的口服抗血小板藥物治療心血管疾病的作用機制和臨床應用，探討了面臨的挑戰(zhàn)，介紹了應對策略，旨在為合理使用口服抗血小板藥物，提高治療效果，降低不良反應提供參考。

Cardiovascular disease is one of the leading causes of death and disability worldwide, and oral antiplatelet drugs play an irreplaceable role in prevention and treatment of cardiovascular disease. The clinical application of oral antiplatelet drugs faces challenges such as bleeding risk, drug resistance, individual differences, and compliance with long-term treatment, and needs to develop strategies to address challenges. This article summarizes the mechanisms and clinical applications of common oral antiplatelet drugs in treatment of cardiovascular diseases, explores the challenges faced, and introduces coping strategies, aiming to provide reference for the rational use of oral antiplatelet drugs, improve treatment efficacy, and reduce adverse reaction.

R972

內(nèi)蒙古自治區(qū)自然科學基金項目（2024LHMS08027）