皮膚病已成為影響人類生活質(zhì)量和身心健康的重要疾病，其臨床治療藥物存在作用機(jī)制單一、停藥易復(fù)發(fā)、個(gè)體療效差異較大、長(zhǎng)期不良反應(yīng)大等缺點(diǎn)。黃芩苷是黃芩中的黃酮類化合物，可通過減輕炎癥反應(yīng)、減輕氧化損傷、抑制角質(zhì)形成細(xì)胞過度增殖、保護(hù)皮膚屏障功能、阻止正常皮膚細(xì)胞死亡、防治皮膚癌發(fā)揮防治多種皮膚病變的作用?？偨Y(jié)了黃芩苷治療皮膚病的藥理作用研究進(jìn)展，為黃芩苷臨床應(yīng)用于皮膚病提供思路。

Skin diseases have become an important disease that affects human quality of life and physical and mental health. Their clinical treatment drugs have disadvantages such as a single mechanism, easy recurrence after discontinuation, significant individual efficacy differences, and large long-term adverse reactions. Baicalin is a flavonoid compound in Scutellariae Radix, which can prevent and treat various skin lesions by reducing inflammation response, alleviating oxidative damage, inhibiting excessive proliferation of keratinocytes, protecting skin barrier function, preventing normal skin cell death, and preventing skin cancer. This article summarizes the pharmacological research progress of baicalin in treatment of skin diseases, providing ideas for the clinical application of baicalin in prevention and treatment of skin diseases.

R285.5;R287.7

四川省科技計(jì)劃項(xiàng)目（2018JY0654）