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[摘要]
羅替戈汀為選擇性多巴胺D1/D2/D3受體激動劑,其透皮貼劑是第一個非麥角類多巴胺受體激動劑貼劑。羅替戈汀貼劑24 h有效,能對帕金森病人持續(xù)提供多巴胺能刺激,目前獲得FDA和EMA批準上市。對羅替戈汀貼劑研究情況進行簡要綜述。
[Key word]
[Abstract]
Rotigotine transdermal patch is the first transdermal non-ergot dopamine agonist, which is a selective dopamine D1/D2/D3 receptor agonist. Rotigotine patch is effective over 24 h providing a continuous dopaminergic stimulation in patients with Parkinson’s disease (PD) and is approved for use in treatment of PD by the FDA and EMA. This paper is a review of current status of Rotigotine transdermal patch.
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