近年來海洋天然產(chǎn)物越來越引起科學(xué)家們的關(guān)注。在浩瀚的海洋中存在著大量超乎人們想象的化學(xué)結(jié)構(gòu)新穎、生物活性多樣、作用機(jī)制獨特的次生代謝產(chǎn)物。海洋天然產(chǎn)物已成為發(fā)現(xiàn)重要先導(dǎo)藥物的主要源泉。本文主要探討近年來發(fā)現(xiàn)的重要的海洋天然活性產(chǎn)物以及在新藥開發(fā)中所起的作用。

Marine natural products have increasingly captured the attention of scientists in recent years. There are great amount of secondary metabolites including unique chemical structure, various potent biological activities, and special physiological mechanism in the vast oceans. Marine natural products have become one of the most important resources of novel leading compounds especially for the critical diseases. This article mainly discussed the roles of important marine natural products and development of new drugs.

河北省引進(jìn)留學(xué)人員基金（2008-2010）、河北省自然科學(xué)基金（08B032）、河北省衛(wèi)生廳基金（05089）以及河北省中醫(yī)藥管理局基金（2006053）、河北醫(yī)科大學(xué)教育科學(xué)研究重點課題（09zd-17）資助項目。