[關(guān)鍵詞]
[摘要]
目的:研究四合木Tetraena mongolica的化學(xué)成分。方法:采用硅膠柱色譜、凝膠柱色譜和HPLC制備色譜方法分離純化得到單體化合物,采用有機(jī)波譜方法鑒定化合物結(jié)構(gòu)。結(jié)果:從四合木醋酸乙酯提取物中分離得到5個(gè)化合物,分別為11α,12α:13β,28-diepoxyoleanane-3β-caffeate(1),3β-hydroxy-11α,12α:13β,28-diepoxyoleanane(2),3β-(3,4-dihydroxy-cinnamoyl)- erythrodiol(3),槲皮素(4),(E)-22-(3-(4-hydroxy-3-methoxyphenyl)acryloyloxy)docosanoic acid(5)。結(jié)論:化合物1~5均為首次從該屬中分離得到,化合物1為未見(jiàn)報(bào)道的新化合物,化合物2為新天然產(chǎn)物。
[Key word]
[Abstract]
Objective: To study the chemical constituents from Tetraena mongolica. Methods: Chemical constituents were isolated and purified by repeated column chromatography (silica gel, Toyopearl HW-40C, and preparative HPLC). Their structures were determined by 1H-NMR, 13C-NMR, and 2D-NMR spectra methods. Results: Five compounds were isolated from the EtOAc extract of Tetraena mongolica and their structures were identified as follows: 11α, 12α: 13β, 28- diepoxyoleanane-3β-caffeate (1), 3β-hydroxy-11α, 12α: 13β, 28- diepoxyoleanane (2), 3β-(3, 4-dihydroxycinnamoyl)-erythrodiol (3), quercetin (4), (E)-22-[3- (4-hydroxy- 3-methoxyphenyl)acryloyloxy]docosanoic acid (5). Conclusion: Compounds 1-5 are isolated from this plant for the first time, compound 1 is a new product, and compound 2 is a new natural product.
[中圖分類號(hào)]
[基金項(xiàng)目]