[關(guān)鍵詞]
[摘要]
綜述石杉堿甲的研究進展,分別從作用機制、藥理作用、合成以及結(jié)構(gòu)修飾等方面對石杉堿甲的研究進行總結(jié),并簡述其發(fā)展方向:ZT-1作為石杉堿甲的替代物,已經(jīng)在歐洲完成Ⅱ期臨床,有望成為我國具有自主知識產(chǎn)權(quán),又有希望打入國際市場的創(chuàng)新藥物。
[Key word]
[Abstract]
The research and development of huperzine A are summarized separately by its mechanism, pharmacology, synthesis, and the structure modification and its development direction is outlined in this paper. ZT-1 as a substitute of huperzine A, the Phase II trial in clinic has been completed in Europe. Huperzine A as an innovation drug is expected to enter the international market with the Chinese intellectual property.
[中圖分類號]
[基金項目]