[關(guān)鍵詞]
[摘要]
毒性病理同行評議(peer review)的目的是核實病理診斷和病理解釋的正確性,提高病理報告的質(zhì)量,執(zhí)行的時機通常在試驗總報告完成前。負責同行評議的病理學家將復查足夠的切片和病理數(shù)據(jù),幫助試驗病理學家進一步確認、精煉病理診斷和數(shù)據(jù)解釋。同行評議需篩選復查的材料由試驗病理學家提供,必要時,可臨時成立病理專家小組來解決爭議或分歧。試驗病理學家根據(jù)同行評議討論產(chǎn)生的結(jié)果對病理數(shù)據(jù)和病理報告進行相應修改,并簽署最終病理報告,是唯一對試驗最終病理數(shù)據(jù)和病理報告內(nèi)容負責的人。同行評議病理學家需出具簽名的同行評議報告,報告中描述同行評議的程序,確認試驗病理學家的病理報告是正確、恰如其分地反應病理數(shù)據(jù)。試驗的病理學家也需要在同行評議報告上簽名,以表明同意同行評議病理學家的觀點??偨Y(jié)了毒性病理同行評議當前執(zhí)行的類型和模式推薦,可根據(jù)特定試驗需要而進行改變。
[Key word]
[Abstract]
The aim of peer review on toxicological pathology is to verify and improve the accuracy and quality of pathology diagnoses and data interpretations. The peer review on toxicological pathology is commonly performed before a study report completed. The peer review pathologist will review enough biopsys and pathological data to assist the study pathologist in refining pathology diagnoses and data interpretations. Data supplied by the study pathologist are to be reviewed and selected by the peer review pathologist. The consultations with the additional experts or a pathological panel may be used to resolve discrepancies if necessary. The study pathologist is solely responsible for the content of the final pathological data and reports, modifies the results according to the peer review discussions, and signs the final pathologist’s report. The peer review pathologist should give a signed peer review report with describing the peer review process and confirming that the study pathologist’s report could accurately and appropriately reflect the pathology data. The study pathologist also needs to check back and sign his or her name on the peer review report, which is proved to agree with the peer review pathologist. The types and modes currently implemented by the peer review on toxicological pathology should be recommended and may be modified to meet the demand of a specific study.
[中圖分類號]
[基金項目]