貼劑的溶出度測(cè)定可用于指導(dǎo)貼劑的研究，提高貼劑的研制水平。貼劑的溶出度與其他固體制劑溶出度測(cè)定沒有多大差別，一般的溶出度測(cè)定方法均可用于貼劑的溶出度測(cè)定。通過比較固體制劑溶出度的研究方法，闡述貼劑溶出度測(cè)定的方法、溶出溶劑的選擇、溶出度的檢測(cè)方法、溶出數(shù)據(jù)的處理等，介紹新型制劑透皮貼劑的溶出度研究情況，為貼劑的進(jìn)一步研究提供參考。

The determination of dissolution rate could be used to guide emplastrum research and elevates the research levels. There is little difference of dissolution rate between emplastrum and other solid preparations’, so the ordinary method for dissolution rate determination could be used for emplastrum. Research methods for dissolution rate of solid preparation and emplastrum are compared and determination method, solvent selection, test methods, and data processing of dissolution rate are explained. The dissolution rate of new type transdermal emplastrm is introduced so as to provide the reference for the further research on transdermal emplastrum.

福建省科技重大專項(xiàng)（2009YZ0001-1-3）；福建省醫(yī)學(xué)創(chuàng)新項(xiàng)目（2009-CX-16）