目的 優(yōu)選雷公藤涂膜劑基質(zhì)的組成和配比。方法 采用正交試驗(yàn)法，以外觀質(zhì)量、成膜時(shí)間為指標(biāo)，確定基質(zhì)中不同輔料的最佳配比。結(jié)果 以聚乙烯醇-124、CMC-Na、甘油比例為4∶1∶2制得的涂膜劑最穩(wěn)定。結(jié)論 優(yōu)選得到的配方設(shè)計(jì)合理，制備工藝簡(jiǎn)單，質(zhì)量可控，可以為工業(yè)生產(chǎn)提供理論基礎(chǔ)。

Objective To optimize the metrical composition and its ratio in Tripterygium Plastics. Methods The best ratio of different materials in the matrix was determined by orthogonal test, using appearance quality and film-forming time as index. Results The best ratio of PVA-124, CMC-Na, and glycerol for making the most stable plaster was 4:1:2. Conclusion The optimized formulation is well designed with simple preparation process and controllable quality, which could provide a theoretical basis for industrial production.

福建省科技重大專項(xiàng)（2009YZ0001-1-3）；福建省醫(yī)學(xué)創(chuàng)新項(xiàng)目（2009-CX-16）；福建省省屬公益類科研院所基本科研專項(xiàng)（2011R1034-3）