目的 通過(guò)藥理實(shí)驗(yàn)確定橢圓葉花錨利膽作用的有效部位，并對(duì)其進(jìn)行成分分離與鑒定。方法 采用膽管引流法試驗(yàn)橢圓葉花錨的利膽作用，并確定了有效部位。再利用硅膠柱色譜、ODS、葡聚糖凝膠等色譜手段分離，通過(guò)¹H-NMR、¹³C-NMR等波譜技術(shù)確定化合物的結(jié)構(gòu)。結(jié)果 從橢圓葉花錨利膽有效部位分離得到了9個(gè)化合物，分別為2，3，5-trimethoxy- 1-O-primevero-syloxyxanthone（1）、2，3，4，5-etramethoxy-1-O-primeverosyloxyxanthone（2）、l，8-dihydroxy-3，5-dimethoxanthone（3）、2，3，4，5，7-pentamethoxy-1-O-primeverosyloxyxanthone（4）、2，3，4，7-etramethoxy-1-O-primeverosyl- oxyxanthone（5）、木犀草苷（6）、木犀草素（7）、齊墩果酸（8）、熊果酸（9）。結(jié)論 其中化合物3為首次從橢圓葉花錨中分得。

Objective To investigate the chemical constituents from Halenia elliptica, which have been confirmed choleretic effect. Methods Biliary drainage method was used to test the choleretic effect of H. elliptica and the compounds were identified. The compounds were isolated by chromatography (silica gel, ODS, and HPLC) and identified on the basis of physicochemical constants and spectral analysis (¹H-NMR and ¹³C-NMR). Results Nine sesquiterpenoids were isolated and their structures were identified as 2,3,5-trimethoxy-1-O-primeveros-yloxyxanthone (1), 2,3,4,5-etramethoxy-1-O-primeverosyloxyxanthone (2), l,8-dihydroxy-3,5- dimethoxanthone (3), 2,3,4,5,7-pentamethoxy-1-O-primeverosy-loxyxanthone (4), 2,3,4,7-etramethoxy-1-O-primeverosyl- oxyxanthone (5), cinaroside (6), luteolin (7), anolic acid (8), and ursolic acid (9). Conclusion Compound 3 is isolated from H. elliptica for the first time.