Lipinski規(guī)則是藥物分子設計和藥物篩選常用的規(guī)則之一。從口服和非口服藥物兩個方面舉例說明它的效用，同時指出它在非口服藥物中的局限性和口服藥物中發(fā)展的前景，旨在為能夠正確認識和恰當使用該原則提供參考。

Lipinski’s rule is one of the common rules for drug molecular design and compound screening. This review summarizes the applications of theses rules in oral and non-oral drugs, on where their shortcomings in non-oral drugs and their prospect in oral drugs are pointed out simultaneously for the purpose of its being comprehended correctly and being used efficiently.