近年來糖尿病的發(fā)病率越來越高，對其研究也成為一大熱點。綜述治療糖尿病的熱點靶點在最近幾年的研究進展，主要包括新型葡萄糖-鈉協(xié)同轉(zhuǎn)運蛋白2（SGLT2）、胰高血糖素樣肽-1（GLP-1）、二肽基肽酶Ⅳ（DPP-Ⅳ）、過氧化物酶體增殖活化受體（PPAR）、蛋白酪氨酸磷酸酶-1B（PTP-1B）等，以期為其進一步研究和臨床應(yīng)用提供參考。

The incidence of diabetes mellitus (DM) is becoming greater and study on it has become a hot topic in recent years. This article showed the latest progress in study on the targets of DM, such as SGLT2, GLP-1, DPP-Ⅳ, PPAR, and PTP-1B, so as to provide the reference for the further research and clinical application of drug used in treatment of DM.