目的 對ADVIA 2120血細胞分析儀的動物血細胞分析性能進行評價。方法 對該儀器的準確度、精密度、線性和攜帶污染率進行評價，并與Hemavet 950FS動物血細胞分析儀測定結(jié)果及人工白細胞分類鏡檢結(jié)果進行比較。結(jié)果 該儀器的準確度、批內(nèi)和批間精密度、攜帶污染率和線性均在允許范圍內(nèi)；與Hemavet 950FS動物血細胞分析儀測定結(jié)果相關(guān)性白細胞（WBC）、紅細胞（RBC）、血紅蛋白（HGB）、血小板（PLT）較好，紅細胞壓積（HCT）較差；白細胞分類測定結(jié)果與人工顯微鏡分類比較，中性粒細胞、淋巴細胞、嗜酸粒細胞相關(guān)性較好，單核細胞、嗜堿粒細胞相關(guān)性較差。結(jié)論 ADVIA 2120全自動血細胞分析儀在測定動物全血樣本時準確度、精密度、線性較好，攜帶污染率低，有較強的篩選能力，是一臺性能良好的全自動血細胞分析儀，可以滿足藥物安全性評價課題動物血液樣本分析的需要。

Objective To evaluate the performance of ADVIA 2120 Hematology Analyzer on blood cell analysis of common laboratory animals. Methods The blood samples were analysed by ADVIA 2120 Hematology Analyzer in terms of accuracy, precision, linearity, and the contamination rate. The results were compared with those of Hemavet 950FS Blood Cell Counter as well as manual blood smears under microscopy. Results The values of the accuracy, precision, linearity, and the contamination rate were all below the qualified standardization. ADVIA 2120 had a good correlation with Hemavet 950FS in WBC, RBC, HGB, and PLT. It also correlated very well with the manual blood smears under microscopy such as neutrophil, lymphocyte, and eosinophil, although some differences were observed in the results of monocyte and basophil. Conclusion The performance of ADVIA 2120 is good and reliable. It could satisfy the hematological analysis of drug evaluation studies.