近年來，腦缺血的炎癥反應引起了越來越多學者的關(guān)注。炎癥反應是缺血性腦損傷的重要病理生理機制之一，參與缺血性腦卒中的發(fā)生、發(fā)展，與危及生命的并發(fā)癥相關(guān)，從而構(gòu)成了缺血性損傷的基礎。就腦缺血有關(guān)的炎性因子及以白細胞介素（IL）-1、IL-8、IL-10、細胞間黏附分子（ICAM）-1、腫瘤壞死因子（TNF）-α和黑皮質(zhì)素（MC）4為靶點的抗腦缺血藥物的最新研究進展作一綜述。

In recent years, the inflammatory reaction of cerebral ischemia has attracted more and more attention of the scholars. Inflammation is one of the important pathophysiological mechanisms of ischemic brain damage, which is involved in the occurrence and development of ischemic stroke and relative with life-threatening complication accompanying ischemic stroke. Additionally, inflammatory factors produced by cerebral ischemia constitute the basis of ischemic injury. This review summarizes the latest research development of some kinds of inflammatory factors related to cerebral ischemia and IL-1, IL-8, IL-10, ICAM-1, TNF-alpha and MC4 as a target for anti-cerebral ischemic drug.