目前藥動學研究方興末艾，國內(nèi)對藥動學技術要求越來越高。綜述了外用制劑的藥物吸收、分布、代謝和排泄等過程各自的研究進展；對外用制劑的應用現(xiàn)狀和代謝特點進行了介紹，重點歸納了藥物有效成分的藥動學研究方法和檢測技術。同時還指出藥動學研究的重要性和今后外用制劑藥動學研究中應該解決的問題。

At present, pharmacokinetic research is still at the exploratory stage, and the domestic demand for pharmacokinetic technique is increasing. The research progress on drug absorption, distribution, metabolism, and excretion of external preparation were reviewed; Application status and metabolic characteristics of external preparation were introduced; And the pharmacokinetic study and detection methods of effective ingredient were mainly summarized. At the same time, the paper also pointed out the importance of future pharmacokinetic studies and the problems to be solved.

福建省科技重大專項（2009YZ0001-1-3）；福建省醫(yī)學創(chuàng)新項目（2009-CX-16）；福建省省屬公益類科研院所基本科研專項（2011R1034-3）