目的 探討劍花提取物的止咳、祛痰、平喘功效。方法 通過動(dòng)物模型引咳、祛痰和引喘實(shí)驗(yàn)研究劍花止咳、祛痰、平喘效果。實(shí)驗(yàn)分為對(duì)照組，劍花提取物低、中、高劑量組及陽性藥組。結(jié)果 與對(duì)照組比較，高、中、低劑量的2種劍花提取物均能顯著減少濃氨水所致小鼠咳嗽次數(shù)（P＜0.05、0.01）；劍花水提物和劍花醇提物中、高劑量組能明顯增加小鼠呼吸道的酚紅排泄量（P＜0.05、0.01）；劍花水提物和劍花醇提物高劑量組能顯著延長枸櫞酸所致豚鼠的哮喘潛伏期（P＜0.05）。結(jié)論 劍花提取物具有明顯的止咳、祛痰、平喘作用。

Objective To study the antitussive, apophlegmatic, and anti-asthmatic effects of the extract from Hylocerei Undati Flos (EHUF). Methods The antitussive, apophlegmatic, and anti-asthmatic effects of EHUF were observed using cough-inducing, eliminating phlegm, and asthma-inducing mouse models. Normal mice were randomly divided into control, positive control, low-, mid-, and high-dose EHUF groups. Results Compared with the control group, high-, mid-, and low-dose of two types of EHUF could decrease the cough rate significantly in mice induced by ammonia solution (P < 0.05, 0.01); Aqueous EHUF and alcohol EHUF in mid- and high-dose could increase the excretion of phenolsulfonphthalein significantly in the respiratory tract of mice (P < 0.05, 0.01); Aqueous EHUF and alcohol EHUF in high-dose could also prolong the asthma latency period resulted from citric acid in guinea pigs significantly (P < 0.05). Conclusion The EHUF has significant antitussive, apophlegmatic, and anti-asthmatic effects.

廣西自然科學(xué)基金項(xiàng)目（桂科自0991264）