目的 均勻設(shè)計(jì)法優(yōu)選連翹超微粉碎工藝技術(shù)參數(shù)。方法 采用單因素考察各粉碎工藝參數(shù)的范圍，結(jié)合均勻設(shè)計(jì)、逐步回歸法優(yōu)選超微粉碎工藝條件。結(jié)果 逐步回歸方程為Y＝41.083－1.029X₂，r＝0.999 8；參照粉碎工藝參數(shù)范圍及生產(chǎn)實(shí)際，選擇連翹超微粉碎工藝條件為粉碎時(shí)間18 min，溫度?10～10 ℃，水分5%～9%，介質(zhì)填充率60%～70%，預(yù)測(cè)粒徑D₅₀為22.56 μm，驗(yàn)證粒徑D₅₀為22.81 μm。結(jié)論 超微粉碎工藝條件參數(shù)與粒徑相關(guān)性良好，均勻設(shè)計(jì)法對(duì)超微粉碎工藝具有較好的指導(dǎo)意義。

Objective To optimize the technical parameters of ultramicro comminution for Forsythia suspensa by uniform design. Methods The scope of each comminution technology parameter was studied by using single-factor test, and the condition of ultramicro comminution technology was optimized by uniform design and stepwise regression. Results The stepwise regression equation was Y = 41.083－1.029X₂, r = 0.999 8; According to the scope of each comminution technology parameter and the actual production conditions, the optimized technical conditions of ultramicro powder grinding of Forsythia suspense were as follows: grinding time 18 min, grinding temperature ?10—10 ℃, water content 5%—9%, medium filling rate 60%—70%, predicted particle diameter D₅₀ 22.56 μm, validation particle diameter D₅₀ 22.81 μm, which revealed that this equation had good practical guidance. Conclusion The relationship between ultramicro comminution technical parameters and particle diameter is very good, and the uniform design could guide the ultramicro comminution technology.

湖南省科技廳重點(diǎn)項(xiàng)目（06FJ2005）