目的 優(yōu)選益氣養(yǎng)心顆粒中丹參提取工藝。方法 以丹參酮Ⅱ_A、丹酚酸B的提取量和提取液浸膏得率為考察指標(biāo)，采用正交設(shè)計(jì)，考察溶劑用量、提取次數(shù)、提取時(shí)間等對(duì)提取效果的影響。結(jié)果 最佳提取工藝為用10倍量的50%乙醇提取3次，每次1 h。結(jié)論 優(yōu)選的純化工藝簡(jiǎn)單易行，適用于實(shí)際生產(chǎn)。

Objective To optimize the extraction technology of Salvia Miltiorrhizae Radix et Rhizoma in Yiqi Yangxin Granule. Methods Using orthogonal test design, the effects of solvent amount, extracting times and extracting time on extraction were investigated using the amounts and extract yields of tanshinone II_A and salvianocilic acid B as indexes. Results The optimum extraction parameters were as follow: 10 times of 50% ethanol, extracting for 3 times and 1 h each time. Conclusion The purification process is simple and suitable for practical production.