[關(guān)鍵詞]
[摘要]
川芎、當(dāng)歸是已知作用較強(qiáng)的活血化瘀中藥,由其組成的復(fù)方芎歸滴丸(舒腦欣滴丸)能增加實(shí)驗(yàn)動(dòng)物的腦血流量、降低血黏度、保護(hù)心臟、預(yù)防急性腦梗死、抑制海馬神經(jīng)元缺氧損傷,還能下調(diào)腦干c-fos基因mRNA的表達(dá),可以用于治療缺血性腦血管病、偏頭痛、血管性老年癡呆等,具有廣闊的臨床應(yīng)用前景。
[Key word]
[Abstract]
Chuanxiong Rhizoma and Angelica Sinensis Radix are known as blood circulation drugs with relatively strong pharmacological effects. Xionggui Dripping Pills (Shunaoxin Dripping Pills) which are composed of Chuanxiong Rhizoma and Angelica Sinensis Radix are able to increase the cerebral blood flow of experimental animals, reduce blood viscosity, protect the heart, prevent acute cerebral infarction, inhibit hippocampal neurons hypoxic injury, and down-regulate c-fos gene mRNA expression. Therefore, the medicine can be used in the treatment of ischemic cerebrovascular disease, hemicrania, vascular dementia,which has the broad clinical application prospects.
[中圖分類(lèi)號(hào)]
[基金項(xiàng)目]