中藥口服液屬于中成藥液體制劑，澄明度好的口服液一般內(nèi)在質(zhì)量也比較優(yōu)良。為了更好地控制中藥口服液的質(zhì)量，需要在制劑工藝中去除雜質(zhì)以提高澄明度。目前提高中藥口服液澄明度的方法主要有醇沉法、高速離心法、膜分離法、大孔吸附樹脂法、澄清劑吸附法、明膠法、調(diào)節(jié)pH值法等。綜述了近年來常用的改善中藥口服液澄明度的新技術、新工藝及其在生產(chǎn)中的應用情況。

Chinese materia medica oral liquid (CMMOL) belongs to the proprietary Chinese medicine liquid preparation. CMMOL with good clarity also has good quality. In order to better control the quality of the CMMOL, we need to remove the impurities in the preparation process in order to improve clarity. The methods to improve clarity of CMMOL are alcohol sinking method, high speed centrifugation, membrane separation, macroporous adsorption resin method, adsorption method, gelatin clarification agent, adjusting pH, and so on. In recent years, new technique and technology for the improvement of CMMOL clarity and its application in the production are reviewed.