目的 對(duì)河北省滄州中西醫(yī)結(jié)合醫(yī)院口服抗高血壓藥物的臨床應(yīng)用情況進(jìn)行分析, 為合理用藥提供參考。方法 對(duì)該院2011年1月－2013年12月門(mén)診口服抗高血壓藥的品種、銷(xiāo)售額、用藥頻度(DDDs)等進(jìn)行統(tǒng)計(jì)分析。結(jié)果 3年里該院口服抗高血壓藥的銷(xiāo)售額和用藥頻度顯著上升, 以鈣通道阻滯劑類(lèi)、血管緊張素轉(zhuǎn)換酶抑制劑類(lèi)、血管緊張素Ⅱ受體拮抗劑類(lèi)為主, 單用品種DDDs排名前3位的依次是氨氯地平、硝苯地平、吲達(dá)帕胺。結(jié)論 該院口服抗高血壓藥應(yīng)用情況基本合理。

Objective To investigate and analyze the application condition of oral antihypertensive drugs in Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine of Hebei Province, and to provide the basis for clinical treatment. Methods The application conditions of oral antihypertensive drugs in the hospital were evaluated in the aspect of drug classification, sales amount, and defined daily dose system (DDDs) from January 2011 to December 2013. Results In recent three years, the consumption sum and DDDs of oral antihypertensive drugs were significantly increased in the hospital, especially the calcium channel blockers, angiotensin converting enzyme inhibiton, and angiotensin Ⅱ receptor antagonists. The top three oral antihypertensive drugs were Amlodipine, Nifedipine, and Indapamide in the term of DDDs. Conclusion The application of oral antihypertensive drugs is reasonable in outpatient in the hospital.

滄州市科技計(jì)劃項(xiàng)目(131302026)