目的 探討美托洛爾治療慢性充血性心力衰竭左心室扭轉(zhuǎn)異?；颊叩呐R床療效及應(yīng)用價(jià)值.方法 選擇北京市昌平區(qū)醫(yī)院治療的慢性充血性心力衰竭左心室扭轉(zhuǎn)異?；颊?4例,采取隨機(jī)數(shù)字表法分為觀察組和對(duì)照組,每組各42例.對(duì)照組給予常規(guī)治療,觀察組在對(duì)照組基礎(chǔ)上聯(lián)合美托洛爾治療,記錄兩組臨床療效.記錄兩組患者治療前后左心室射血分?jǐn)?shù)和左心室舒張末期內(nèi)徑變化.計(jì)算心底位旋轉(zhuǎn)角度峰值、心尖位旋轉(zhuǎn)角度峰值、扭轉(zhuǎn)角度峰值變化情況.結(jié)果 觀察組治療顯效22例,有效17例,無效3例;對(duì)照組治療顯效10例,有效21例,無效11例,組間對(duì)比差異有統(tǒng)計(jì)學(xué)意義(P <0.05).觀察組治療后左心室射血分?jǐn)?shù)為(49.38±5.97)%,左心室舒張末期內(nèi)徑為(52.38±4.01)mm;對(duì)照組治療后左心室射血分?jǐn)?shù)為(44.78±4.46)%,左心室舒張末期內(nèi)徑為(58.23±5.32)mm,組間對(duì)比差異有統(tǒng)計(jì)學(xué)意義(P <0.05).觀察組治療后心尖位旋轉(zhuǎn)峰值(5.81±2.86)°,心底位旋轉(zhuǎn)峰值(-3.79±2.75)°,左心室扭轉(zhuǎn)峰值(9.24±3.86)°;對(duì)照組治療后心尖位旋轉(zhuǎn)峰值(3.65±1.34)°,心底位旋轉(zhuǎn)峰值(-2.82±1.50)°,左心室扭轉(zhuǎn)峰值(5.62±1.68)°,組間對(duì)比差異有統(tǒng)計(jì)學(xué)意義(P <0.05).結(jié)論 采用美托洛爾治療慢性充血性心力衰竭左心室扭轉(zhuǎn)異常療效可靠,能夠提高患者心臟功能,同時(shí)可以改善左心室重構(gòu)增強(qiáng)左心室扭轉(zhuǎn),改善患者預(yù)后,值得在臨床上大力推廣使用.

Objective To study the clinical efficacy and application value of metoprolol in the treatment of left ventricular torsion abnormality (LVTA) in patients with chronic heart failure (CHF). Methods The LVTA patients with CHF (84 cases) in Changping Hospital were randomly divided into observation group and control group, the patients in control group were given conventional treatment, and the patients in observation group were given metoprolol treatment based on control group. The clinical curative effects of two groups were recorded. Results The observation group had 22 cases treatment markedly, 17 cases effective, and 3 cases invalid; In the control group there were 10 cases of treatment, 21 cases effective, and 11 cases invalid, the difference was statistically significant between the groups (P <0.05). In the observation group, after treatment, left ventricular ejection fraction was (49.38±5.97)%, left ventricular end diastolic diameter was (52.38±4.01) mm. In the control group, left ventricular ejection fraction after treatment was (44.78±4.46)%, left ventricular end diastolic diameter was (58.23±5.32) mm, and the difference was statistically significant between the groups (P <0.05). In the observation group after treatment, apical rotation peak was (5.81±2.86) °, the bottom of my heart bit rotation peak was (-3.79±2.75) °, left ventricular torsion peak was (9.24±3.86) °. In the control group, apical rotation peak group therapy was (3.65±1.34) °, the bottom of my heart bit rotation peak was (-2.82±1.50) °, left ventricular torsion peak was (5.62±1.68) °, and the difference was statistically significant between the groups (P <0.05). Conclusion The curative effect of metoprolol in treatment of LVTA in patients with CHF was reliable, metoprolol could improve heart function of patients, improve left ventricular remodeling, enhance left ventricular torsion, and improve the prognosis of patients. which is worth to popularize in clinical use.