目的 探討舒樂安定的助眠效果以及藥物依賴情況.方法 選取2012年4月—2014年3月在?？谑械谒娜嗣襻t(yī)院治療的失眠癥患者124例,隨機分為觀察組(n＝62,給予舒樂安定)和對照組(n＝62,給予阿米替林),觀察兩組療效以及藥物依賴情況,同時采用紐芬蘭紀念大學幸福度量表,對兩組患者治療前后進行問卷調(diào)查.結(jié)果 觀察組總有效率為93.55%,明顯高于對照組的79.03%,差異有統(tǒng)計學意義(P <0.05);觀察組和對照組治療后幸福度總分均較治療前有所增高,差異有統(tǒng)計學意義(P <0.05);觀察組治療后幸福度總分為(37.18±5.28)分,明顯高于對照組的(30.22±4.17)分,差異有統(tǒng)計學意義(P <0.05);觀察組有33例產(chǎn)生藥物依賴性,占53.23%,而對照組有18例產(chǎn)生藥物依賴性,占29.03%,兩組差異有統(tǒng)計學意義(P <0.05).結(jié)論 舒樂安定片治療失眠癥有較好的療效,但仍存在藥物依賴性的問題.

Objective To investigate the hypnosis effect and drug dependency of Estazolam Tablet. Methods From April 2012 to March 2014 in Fourth People's Hospital of Haikou, the insomnia patients (124 cases) were randomly divided into observation group (n= 62, estazolam) and control group (n = 62, amitriptyline), the curative effect and drug dependence in two groups were observed, and at the same time, the patients in two groups before and after treatment were investigated by questionnaire survey using Memorial University of Newfoundland Happiness measure table. Results The total effective rate of observation group was 93.55%, significantly higher than that in the control group (79.03%), and the difference was statistically significant (P <0.05); The happiness scores of observation group and control group after treatment were increased than those before treatment, and the difference was statistically significant (P <0.05); The happiness score of patients in the observation group was (37.18 ± 5.28), significantly higher than that of the control group (30.22 ± 4.17), and the difference was statistically significant (P <0.05); There were 33 cases in observation group producing drug dependence, accounted for 53.23%, while the control group had 18 cases producing drug dependence, accounted for 29.03%, with significant difference between two groups (P <0.05). Conclusion Estazolam Tablet in the treatment of insomnia has a good effect, but there is still the problem of drug dependence.