現(xiàn)代研究表明,何首烏化學(xué)成分包括蒽醌類、二苯乙烯苷類、磷脂類、酚類和黃酮類等。具有抗衰老、提高免疫力、降血脂、抗動(dòng)脈粥樣硬化、抗炎、抗菌、抗癌、抗誘變等藥理作用,毒理作用主要表現(xiàn)為肝臟毒性。以"何首烏"、"化學(xué)成分"、"藥理學(xué)"、"毒理學(xué)"、"Polygonum multiflorum"、"Pharmacology"、"Toxicology"為關(guān)鍵詞檢索中英文數(shù)據(jù)庫,組合查詢2000年至2015年在Pubmed、中國知網(wǎng)全文數(shù)據(jù)庫、維普中文期刊全文數(shù)據(jù)庫、萬方數(shù)據(jù)庫和讀秀數(shù)據(jù)庫中有關(guān)何首烏的化學(xué)成分、藥理作用、毒理學(xué)的文獻(xiàn)并進(jìn)行分析、總結(jié)和歸納,為進(jìn)一步研究何首烏化學(xué)成分、藥理學(xué)與毒理學(xué)提供參考,為后續(xù)藥學(xué)工作者提供文獻(xiàn)依據(jù)和研究思路。

Chemical constituents of Polygonum multiflorum including anthraquinone glycosides, two styrene, phospholipids, phenols and flavonoids etc. With anti-aging, improve immunity, lowering blood lipids, anti atherosclerosis, anti-inflammatory, antibacterial, anticancer, anti mutagenic and other pharmacological effects, toxicity is mainly manifested as liver toxicity. To Polygonum multiflorum, pharmacology, toxicology as the keywords search in the database, combined query from 2000 to 2015 in PubMed, CNKI full text number according to library, VIP Chinese journal full text database, Wanfang database and Duxiu database related to Polygonum multiflorum chemical constituents, pharmacological activities and toxicology of literature and analysis, summary and induction. To investigate and summarize Polygonum multiflorum chemical constituents, pharmacological and toxicological studies, to provide literature basis and research ideas for further pharmaceutical workers.