目的 分析研究聯(lián)合使用血栓通注射液與高壓氧對腦梗死患者的血脂及血液流變學的影響。方法 選擇2012年8月-2014年4月楊凌示范區(qū)醫(yī)院收治的腦梗死患者92例為研究對象,隨機分為兩組。對照組給予高壓氧治療,實驗組給予高壓氧聯(lián)合血栓通注射液治療,觀察患者血脂及血液流變學指標的變化。結果 治療后,實驗組患者三酰甘油(TG)、總膽固醇(TC)、低密度脂蛋白膽固醇(LDL-C)、脂蛋白a(LP-a)均顯著低于對照組患者,高密度脂蛋白膽固醇(HDL-C)顯著高于對照組,差異有統(tǒng)計學意義(P<0.05)。實驗組與對照組患者治療后的載脂蛋白A1(ApoA1)、載脂蛋白B(ApoB)對比差異無統(tǒng)計學意義。治療后,實驗組患者血漿黏度、紅細胞壓積(Hct)及血沉(ESR)均低于對照組患者,差異有統(tǒng)計學意義(P<0.05)。結論 聯(lián)合使用高壓氧與血栓通注射液有助于改善腦梗死患者的血脂和血液流變學,具有積極的臨床意義。

Objective To analyze the effect of Xueshuantong Injection combined with hyperbaric oxygen in patients with cerebral infarction. Methods The research object was chosen from the patients treated in Yangling Demonstration Zone Hospital Yang ling from August 2012 to April 2014. There were 92 patients participated in the research and divided them into two groups randomly:the experimental group and the control group. The control group only received the hyperbaric oxygen therapy, whereas the patients in experimental group were treated with hyperbaric oxygen combined with Xueshuantong Injection. The changes of blood lipid and blood rheology indexes were compared in the patients. Results After treatment, the triglyceride glycerol (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), and lipoprotein a (LP-a) of the patients in experimental group were significantly lower than those of the patients in control group, the high density lipoprotein cholesterol (HDL-C) was significantly higher than that of the control group. The difference was statistically significant (P<0.05). There was no significant difference of apolipoprotein A1(ApoA1) and apolipoprotein B (ApoB) between the experimental group and control group of patients after treatment. After treatment, the plasma viscosity, red blood cell hematocrit (HCT), and erythrocyte sedimentation rate (ESR) of patients in experimental group were significantly lower than those in the control group, and the difference was statistically significant (P<0.05). Conclusion Using hyperbaric oxygen combined with Xueshuantong Injection is helpful in improving the serum lipid and hemorheology of patients with cerebral infarction.