敗醬草為我國(guó)傳統(tǒng)中藥,始載于《神農(nóng)本草經(jīng)》,具有清熱解毒、利濕排膿、活血化瘀的功效。臨床上常用于治療腸癰、肺癰、癰腫瘡毒和產(chǎn)后瘀阻腹痛等癥。近年來(lái)化學(xué)成分研究顯示敗醬草中含有三萜類、黃酮類、環(huán)烯醚萜類、甾醇、香豆素及有機(jī)酸類,藥理研究發(fā)現(xiàn)敗醬草具有抑菌、鎮(zhèn)靜、胃腸、抗腫瘤、抗氧化及抗前列腺增生的作用。其來(lái)源植物黃花敗醬草和白花敗醬草的化學(xué)成分和藥理作用存在一定差異,因此對(duì)兩種來(lái)源敗醬草的化學(xué)成分及藥理作用的研究情況進(jìn)行綜述,為深度研究與開發(fā)提供參考。

Patriniae Herba is a traditional Chinese medicine, originally recorded in "Shengnong's Herbal Classic" with clearing heat and detoxicating, removing dampness and apocenosis, and promoting blood circulation to remove blood stasis. Commonly it was used in clinical treatment of lung abscess, appendicitis, carbuncle sore, and postpartum blood stasis symptoms such as abdominal pain. In recent years, large quantities of triterpenes had been isolated from the plant, together with other types of active principles, such as flavonoids, iridoids, sterols, coumarins, and organic acids. Patriniae Herba had the antibacterial, sedation, gastrointestinal, antitumor, anti-oxidant, and antihyperplasia effects. There are some differences in the chemical constituents and pharmacological effects between Patrinia scabiosaefolia and P. villosa, so this paper reviewed the chemical composition and pharmacological action of two sources of Patriniae Herba, in order to provide reference for the research and development of Patriniae Herba.