蒼術(shù)及其有效成分的消化系統(tǒng)藥理作用主要包括抗胃潰瘍、促進胃排空、調(diào)節(jié)胃腸推進運動、抗腹瀉、利膽和保肝以及提高消化吸收功能作用。蒼術(shù)可通過阻斷H₂受體抑制胃酸分泌，抑制胃組織炎性因子過度表達產(chǎn)生抗胃潰瘍作用。蒼術(shù)還可通過阻斷5-羥色胺受體，提高血清和胃組織的胃泌素、三葉因子水平，增加胃黏膜血流量，促進胃黏膜生長和修復(fù)，產(chǎn)生抗?jié)冏饔?。而蒼術(shù)促進胃排空和胃腸推進運動主要與其抑制中樞促皮質(zhì)素釋放因子的釋放和刺激迷走神經(jīng)以及促進胃腸激素胃泌素、胃動素釋放，抑制血管活性腸肽釋放和5-羥色胺-3受體，提高胃腸組織Cajal間質(zhì)細胞數(shù)量有關(guān)?？寡鬃饔檬巧n術(shù)抗腹瀉的主要機制。

The pharmacologic action of Atractylodis Rhizoma and its effective constituents in digestive system includes mainly anti-ulcer activity, acceleration of gastric emptying, regulation of gastrointestinal propellant movement, antidiarrheal effect, choleretic effect, hepatoprotection, and promotion of digestive and absorptive function. Atractylodis Rhizoma decreases gastric acid secretion via blockade of H₂-receptor, and inhibits overexpression of inflammatory cytokines in gastric tissues to produce anti-ulcer effect. Atractylodis Rhizoma increases gastric mucosal blood flow, and improves growth and reparation of gastric mucosa to produce anti-ulcer effect by blockade of 5-TH receptor, and elevating levels of gastrin and trefoil factor in serum and gastric tissues. Atractylodis Rhizoma accelerating gastric emptying and gastrointestinal propellant movement is relative to decreasing release of central corticotropin-releasing factor, and stimulating vagal nerve, and promoting secretion of gastrin and motilin, and inhibiting secretion of vasoactive intestinal peptide, and blocking 5-HT-3receptor, and increasing amount of interstitial cell of Cajal.