目的 探討瑞芬太尼與芬太尼在小兒先天性心臟病介入手術(shù)麻醉中的效果。方法 80例小兒先天性心臟病患兒入院后被分為兩組，對(duì)照組（40例）給予芬太尼麻醉，觀察組（40例）給予瑞芬太尼麻醉，依據(jù)麻醉前后不同時(shí)間的收縮壓（SDP）、舒張壓（DBP）、心率（HR），兩種麻醉藥物的拔管時(shí)間、蘇醒時(shí)間及麻醉用藥量及麻醉期間患兒出現(xiàn)的不良反應(yīng)情況，評(píng)價(jià)瑞芬太尼與芬太尼在小兒先天性心臟病介入手術(shù)麻醉中的效果。結(jié)果 與誘導(dǎo)前的基礎(chǔ)值相比，麻醉藥物誘導(dǎo)后兩組SDP、DBP值均降低，組內(nèi)比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；兩組HR水平與誘導(dǎo)前的基礎(chǔ)值相比，差異無(wú)統(tǒng)計(jì)學(xué)意義。觀察組拔管時(shí)間、蘇醒時(shí)間均短于對(duì)照組，組間差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；但觀察組麻醉藥物用量多于對(duì)照組，兩組比較差異顯著（P<0.05）。麻醉期間，兩組不良反應(yīng)率相比，差異無(wú)統(tǒng)計(jì)學(xué)意義。結(jié)論 瑞芬太尼對(duì)小兒先天性心臟介入手術(shù)麻醉效果好，對(duì)心功能的影響較小，術(shù)后能早期拔管，副作用較小，是目前臨床上一種理想的麻醉藥物。

Objective Discuss the anesthetic effect of remifentanil and fentanyl on interventional surgery for children with congenital heart disease. Methods 80 patients with congenital heart disease were selected, they were divided into two groups randomly. The control group (40 cases) was given fentanyl anesthesia. The observation group (40 cases) was given remifentanil anesthesia. Observe and record SDP, DBP, HR at different time of anesthesia, extubation time, recovery time and dosage of anesthesia and adverse reaction during anesthesia to evaluate the anesthetic effect of remifentanil and fentanyl on interventional surgery for children with congenital heart disease. Results Compared with the basic value before induction of anesthesia, the SDP, DBP of two groups were decreased after induction (P<0.05). There was no significant difference on HR level between two groups before and after induction. The extubation time, recovery time of observation group was shorter than that of the control group. However, the amount of anesthesia drug in the observation group was higher than that of the control group (P<0.05). During anesthesia, there was no significant difference on adverse reactions between two groups. Conclusion The anesthetic effect of remifentanil on interventional surgery for children with congenital heart disease is good, and it has little effect on cardiac function with early extubation and less side effect.