目的 探討胃康寧顆粒與胃復(fù)春片治療慢性萎縮性胃炎（CAG）癌前病變的臨床效果。方法 將安陽(yáng)市第三人民醫(yī)院自2012年1月-2016年12月收治的CAG癌前病變患者85例作為研究對(duì)象，隨機(jī)分為對(duì)照組41例和研究組44例，對(duì)照組給予胃復(fù)春片治療，研究組給予胃康寧顆粒治療，比較兩組治療前后的病理積分及臨床療效。結(jié)果 兩組治療后炎癥、萎縮、腸化生積分均明顯較治療前減小，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；研究組炎癥、腸化生積分明顯小于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。研究組臨床總有效率為90.91%，明顯高于對(duì)照組的75.61%，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 胃康寧顆粒治療CAG癌前病變效果顯著，尤其對(duì)炎癥、腸化生等組織學(xué)變化有明顯的改善作用，臨床應(yīng)用價(jià)值高。

Objective To explore the clinical effect of Weikangling and Weifuchun treatment of chronic atrophic gastritis and precancerous lesions. Methods 85 cases of CAG precancerous lesions treated in our hospital from Jan. 2012 to Dec. 2016 were selected as the research object, and were randomly divided into control group (n=41) and study group (n=44). The control group were given Weifuchun, and the study group were given Wei Kangling. The pathological score and clinical efficacy were compared between the two groups before and after treatment. Results After treatment, inflammation, atrophy, intestinal metaplasia scores of the two groups were significantly decreased than before treatment in addition to dysplasia (P<0.05), and inflammation and intestinal metaplasia in the study group were significantly lower than those in the control group (P<0.05). The total effective rate of the study group was 90.91%, which was higher than 75.61% of the control group (P<0.05). Conclusions The effect of Wei Kangling in treating precancerous lesions of CAG is significant, especially for the histological changes of inflammation and intestinal metaplasia.