[關(guān)鍵詞]
[摘要]
目的 評(píng)價(jià)丹參川芎嗪治療后循環(huán)缺血性眩暈的臨床療效。方法 選擇2015年3月-2017年3月在安徽省中醫(yī)院診治的后循環(huán)缺血性眩暈患者80例,隨機(jī)分為對(duì)照組和觀察組,各40例。對(duì)照組患者口服甲磺酸倍他司汀,6 mg/次,3次/d;治療組靜脈滴注丹參川芎嗪注射液,10 mL/次加入0.9% NaCl 250 mL,1次/d,均用藥2周;觀察兩組患者的療效,并比較兩組治療前后臨床癥狀等的改善程度;檢測(cè)治療前后血黏度、纖維蛋白原等實(shí)驗(yàn)室指標(biāo)的變化。結(jié)果 治療后,治療組患者的總有效率92.5%,對(duì)照組的72.5%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05);血黏度和血纖維蛋白原較治療前均有改善,且治療組改善情況優(yōu)于對(duì)照組,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 丹參川芎嗪注射液治療后循環(huán)缺血性眩暈的臨床療效較好,可以改善腦后循環(huán)血液供應(yīng),值得推廣。
[Key word]
[Abstract]
Objective To observe the clinical effect of Danshen Chuangxiongqin Injection in treatment of posterior circulation ischemia vertigo. Methods Patients (80 cases) with posterior circulation ischemia vertigo attack in Anhui Hospital of Traditional Chinese from March 2015 to March 2017 were randomly divided into control and treatment groups, and each group had 40 cases. Patients in control group were treated by Betahistine mesylate, 6 mg/time (3 times/d) for 2 weeks. Patients in treatment group were iv administered with Danshen Chuangxiongqin Injection (10 mL/d) added into normal saline 250 mL, once daily for 2 weeks. After treatment, the efficacy was evaluated, and the levels of blood viscosity index, fibrinogen in two groups before and after treatment were compared. Results Total effective rate of observation group was 92.5% which was higher than the control group's 72.5% with significant difference (P<0.05). After treatment, the laboratory indexes (levels of blood viscosity, fibrinogen, and so on) were decreased, the improvement degree of these indexes in treatment group were significantly better than those in control group, with significant difference between two groups (P<0.05). Conclusion Danshen Chuangxiongqin Injection has significant effect in treating posterior circulation ischemia vertigo and it is worthy of clinical application and promotion.
[中圖分類號(hào)]
[基金項(xiàng)目]