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[摘要]
目的 探討卡前列素氨丁三醇注射液治療前置胎盤剖宮產(chǎn)產(chǎn)后出血的臨床效果。方法 根據(jù)醫(yī)院數(shù)據(jù)庫的記錄隨機選取2015年1月-2016年6月,河南科技大學第一附屬醫(yī)院收治的65例前置胎盤剖宮產(chǎn)患者作為研究對象,根據(jù)治療方法分成觀察組和對照組,觀察組患者33例,對照組患者32例。胎兒娩出后,胎盤存在粘連、植入,胎盤剝離面廣泛滲血,出血量大于500 mL時,對照組以宮腔填塞碘仿紗條行止血治療,觀察組患者則在對照組治療的方法基礎上,在填塞碘仿紗條的過程中在子宮壁注射卡前列素氨丁三醇注射液250 μg,若患者仍有產(chǎn)生出血現(xiàn)象,可在0.5 h時后行1次注射,但是總注射劑量應在2 mg以下。宮紗放置用時為48 h,取紗前的30 min對其靜脈滴注縮宮素。綜合比較兩組患者產(chǎn)后出血量的改變情況、子宮切除率和治療前后的收縮壓、舒張壓、脈搏跳動以及血氧飽和度的情況。結果 觀察組患者產(chǎn)后2 h、產(chǎn)后24 h的出血量分別為(380.12±12.77)、(461.48±13.33)mL,均少于對照組患者的(952.34±111.65)、1160.7±132.87)mL,差異有統(tǒng)計學意義(P<0.05)。觀察組子宮的切除率為0%,對照組的子宮切除率為9.38%,觀察組的子宮切除率低于對照組,差異有統(tǒng)計學意義(P<0.05)。兩組患者治療后收縮壓、舒張壓較治療前無明顯下降,脈搏次數(shù)、血氧飽和度治療前后提升也不大,組間比較差異無統(tǒng)計學意義。結論 卡前列素氨丁三醇注射液治療前置胎盤剖宮產(chǎn)產(chǎn)后出血效果明顯,能夠很好地控制患者產(chǎn)后的出血量,治療安全性良好,值得推廣。
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[Abstract]
Objective Discuss the clinical effect observation Hemabate combined with Iodoform gauze packing in uterine cavity in treating placenta previa. Methods Retrospective analysis 65 cases patients with placenta previa inspection data from our hospital during January 2015 to June 2016, the patients will be selected by random number table method is divided into research group and the control group, the research goups have 33patients and the control groups have 32 patients. Control group on the basis of the conventional treatment methods with odoform gauze packing in uterine cavity, the research group on the basis of the control group used Hemabate treatment, compared two groups of patients with intraoperative, Uterus resection rate, before and after treatment of systolic pressure, diastolic blood pressure, pulse and blood oxygen saturation. Results The research Group patients after 2 h, 24 h of postpartum haemorrhage amount respectively (380.12 ±12.77), (461.48 ±13.33) mL, less than the control group patients after 2 h, 24 h of postpartum haemorrhage amount respectively (952.34 ±111.65) mL, (1160.7 ±132.87) mL, the difference was statistically significant (P < 0.05), uterus resection rate of observation group was 0%, the control of the uterus resection rate was 9.38%, the team's uterus removal rate is lower than the control group (P < 0.05), the difference was statistically significant. Conclusion Hemabate combined with Iodoform gauze packing in uterine cavity in treating placenta previa effective prevention of cesarean delivery postpartum hemorrhage, high safety, worth clinical promotion.
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