[關(guān)鍵詞]
[摘要]
腫瘤多藥耐藥(multidrug resistance,MDR)對(duì)腫瘤的藥物治療的療效有嚴(yán)重的影響。多藥耐藥擁有十分復(fù)雜的發(fā)生發(fā)展的機(jī)制。通過討論自噬與藥物抗腫瘤時(shí)的相互影響,旨在闡明自噬與腫瘤細(xì)胞多藥耐藥的關(guān)系,為今后抗腫瘤藥物治療的臨床應(yīng)用提供新的思路。
[Key word]
[Abstract]
Tumor multidrug resistance (MDR) has seriously affected the efficacy of drug therapy on tumors. The occurrence of multidrug resistance has a very complex mechanism. In this paper, we discuss the relationship between autophagy and drug anti-tumor, aiming to elucidate the relationship between autophagy and multidrug resistance in tumor cells, and provide new ideas for the clinical application of anticancer drugs.
[中圖分類號(hào)]
[基金項(xiàng)目]
國家自然科學(xué)基金項(xiàng)目(81473280)