建立一種分析國產(chǎn)藥說明書信息差異的程序，可以幫助監(jiān)管人員及時(shí)有效地識(shí)別藥品說明書的信息差異，以督促企業(yè)盡快完善藥品說明書。建立結(jié)構(gòu)化的藥品說明書庫，并設(shè)計(jì)藥品說明書比對(duì)程序和算法，采用余弦相似度文本分析法分析國產(chǎn)藥說明書的信息差異，并與國家藥品不良反應(yīng)（ADR）監(jiān)測(cè)中心建立相關(guān)鏈接，從而讓藥品說明書信息差異分析更加合理，能夠有效提高我國相關(guān)制藥企業(yè)完善藥品說明書的效率。

A program to analyze information discrepancy in domestic drug instructions is established, which helps supervisors to identify information discrepancy in time and effectively, so as to urge enterprises to improve drug instructions as soon as possible. The structured drug description library is established, the algorithm and program is designed, and the information difference of domestic drug instructions were analyzed by using cosine similarity analysis. And there is a link with the national adverse drug reaction (ADR) monitoring center. Therefore, the difference analysis of drug instruction information is more reasonable, and it can effectively improve the efficiency of the related pharmaceutical enterprises in China to improve the drug instruction.

廣東省藥品不良反應(yīng)監(jiān)測(cè)中心；遼寧省教育廳人文社會(huì)科學(xué)研究項(xiàng)目（201610163W05）；沈陽藥科大學(xué)工商管理學(xué)院中青年教師事業(yè)發(fā)展支持計(jì)劃