目的 對比分析阿奇霉素與諾氟沙星治療小兒急性腸胃炎的臨床效果。方法 選擇2014年1月-2015年1月在成都市龍泉驛區(qū)婦幼保健院進(jìn)行診治的小兒急性腸胃炎患者100例，隨機(jī)分為阿奇霉素組與諾氟沙星組，每組各50例。阿奇霉素組靜脈注射阿奇霉素治療，根據(jù)患兒體質(zhì)量每次10 mg/kg，每天1次；諾氟沙星組靜脈注射諾氟沙星注射液治療，每次150 mg，每天2次。比較兩組的臨床治療效果，住院時(shí)間、嘔吐緩解時(shí)間、發(fā)熱緩解時(shí)間、腹瀉緩解時(shí)間以及腹痛緩解時(shí)間。結(jié)果 阿奇霉素組的有效率為98.00%（49/50），明顯高于諾氟沙星組的78.00%（39/50），差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。阿奇霉素組患兒的住院時(shí)間、嘔吐緩解時(shí)間、發(fā)熱緩解時(shí)間、腹瀉緩解時(shí)間以及腹痛緩解時(shí)間均明顯短于諾氟沙星組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。阿奇霉素組的不良反應(yīng)發(fā)生率為4.00%（2/50），與諾氟沙星組的6.00%（3/50）相比無明顯差異。結(jié)論 阿奇霉素對小兒急性腸胃炎的臨床治療效果明顯優(yōu)于諾氟沙星，安全有效，具有較高的臨床應(yīng)用價(jià)值。

Objective To comparethe clinical efficacy of azithromycin and norfloxacin in treatment of acute gastroenteritis in children.Methods Selected 100 cases of patients with acute gastroenteritis who were treated in our hospital from January 2014 toJanuary 2015, divided into two groups randomly. Azithromycin group was treated with intravenous azithromycin, 450 mg per day, 1 times a day, norfloxacin group was treated with norfloxacin, 400 mg per day, 2 times a day. The clinical effects of two groups were compared, the time of hospitalization, the time of wheezing disappearance, the time of cough disappearance, the normal time of body temperature recovery and the time of pulmonary rale disappearance were recorded.Results After treatment, the effective rate of the azithromycin group was 98.00% (49/50), significantly higher than that of the norfloxacin group 78.00% (39/50) (P< 0.05); the time of hospitalization, the time of wheezing disappearance, the time of cough disappearance, the normal time of body temperature recovery and the disappearance time of lung rale in the azithromycin group were significantly shorter than those in the norfloxacin group (P< 0.05); the adverse reaction rate of the azithromycin group was 4.00% (2/50), has no significant difference with the norfloxacin group 6.00% (3/50).Conclusion Azithromycin is superior to norfloxacin in the treatment of acute gastroenteritis in children, which is safe and effective, and has high clinical value.