目的 探討化積片治療小兒厭食的療效和安全性。方法 將50例小兒厭食的患兒隨機(jī)分為試驗(yàn)組和對照組各25例，試驗(yàn)組服用化積片，一次3片，一日2次，對照組服用兒脾醒顆粒，3~5歲一次1.25g，一日3次，6~14歲一次2.5 g，一日3次，療程4周。比較兩組的食欲不振、體質(zhì)量、中醫(yī)證候療效。結(jié)果 服藥4周后，化積片治療小兒厭食食欲不振療效試驗(yàn)組總有效率92%；對照組2總有效率88%，兩組比較差異無統(tǒng)計(jì)學(xué)意義；試驗(yàn)組治療后平均體質(zhì)量（18.37±1.72） kg，對照組（17.43±1.29） kg，兩組間療后比較，差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）；試驗(yàn)組的中醫(yī)證候療效總有效率為96%、對照組為92%，試驗(yàn)組的愈顯率為80%、對照組為68%，兩組比較差異無統(tǒng)計(jì)學(xué)意義。結(jié)論 化積片治療小兒厭食癥在改善食欲不振癥狀，尤其改善患兒體質(zhì)量方面，療效確切，且用藥安全性較好，無不良反應(yīng)發(fā)生，值得在兒科消化科推廣。

Objective To study effect and safety of Huaji Tablets in the treatment of infantile anorexia.Method 50 Cases of infantile anorexia were randomly divided into experimental group and control group (n=25). Experimental group take Huaji Tablets, 3 tablets per time, twice per day. Control group takes erpixing particles. Three to five years old:1.25 g/time, 3 times/day; Six to fourteen years old:2.5 g/time, 3 times/day, 4 weeks of treatment course. Comparison of two groups of loss of appetite, weight and syndromes curative effect.Result After 4 weeks of taking medicine, experimental group of Huaji Tablets in infantile anorexia show effective rate was 92%; For control group, effective rate was 88%, there was no significant difference between the two groups. Average weight for experimental group and control group was (18.37±1.72) kg and (17.43±1.29) kg respectively, comparison between the two groups after treatment, the difference was statistically significant (P< 0.05). Total effective rate and cure rate of syndromes curative effect for experimental group was 96% and 80%, for control group was 92% and 68%, there was no significant difference between the two groups.Conclusion Treatment of Huaji Tablets in infantile anorexia can improve the symptoms of anorexia, especially improve weight for infantile, it is effective and safe, no adverse effects were found, it is worth clinical promotion and application.