目的 建立用于測定注射用益氣復脈（凍干）（YQFM）中總有機酸含量的電位滴定方法。方法 注射用益氣復脈（凍干）用水溶解后，經(jīng)001*1陽離子交換樹脂將鹽還原為酸，以琥珀酸為對照品，用電位滴定法測定益氣復脈中總有機酸的含量。結(jié)果 以琥珀酸計，YQFM中總有機酸滴定精密度RSD 0.42%，穩(wěn)定性RSD 0.84%，重復性RSD 1.88%，平均加樣回收率（n=9）為100.15%，RSD 1.68%。結(jié)論 本實驗所建立的電位滴定方法簡便易行，可操作性強，適用于YQFM中總有機酸的含量測定。

Objective To establish a potentiometric titration analytical method for the determination of the total organic acids in Yiqi Fumai Lyophilized Injection (YQFM). Methods With butanedioic acid as reference, the total organic acids in purified YQFM were detected by potentiometric titration. Result The precision, stability, and repeatability of the method were very good with RSD 0.42%, 0.84%, and 1.88%, respectively. The average recovery (n=9) of the method was 100.15% with RSD 1.68%. Conclusion The method is feasible and reproducible, which is suitable for the determination of the total organic acids in YQFM.