[關鍵詞]
[摘要]
為了了解與掌握網(wǎng)絡毒理學研究方法及其在中藥毒性成分預測中的應用;簡介網(wǎng)絡毒理學的概念,分析了網(wǎng)絡毒理學的研究思路,總結了相關毒性預測工具與軟件,概述了毒性預測的方法與研究思路,重點綜述了網(wǎng)絡毒理學在中藥肝毒性、腎毒性成分、心臟毒性成分與急性毒性成分預測中的具體應用;隨著現(xiàn)代計算機技術的發(fā)展,網(wǎng)絡毒理學已經(jīng)廣泛應用于中醫(yī)藥相關領域,尤其在中藥毒性成分預測中,更是發(fā)揮著重要的作用;隨著中醫(yī)藥的現(xiàn)代化,人們更深刻的認識了中藥的毒性成分,迫切需要用現(xiàn)代技術方法對中藥毒性進行預測與評價,為進一步認識和發(fā)展網(wǎng)絡毒理學及其在中藥毒性成分預測中的應用提供了參考依據(jù)。
[Key word]
[Abstract]
In order to understand and master the research methods of network toxicology and its application in the prediction of Chinese traditional Chinese medicine toxicology. In this paper, we mainly explore the concept of network of toxicology, and analyze the network toxicology research train of thought, summarize the related toxicity prediction tools and software, the toxicity prediction method as well as the research train of thought, the key network toxicology were reviewed in application of prediction of traditional Chinese medicine liver toxicity and kidney toxicity, heart toxicity component and forecasting acute toxicity composition. With the development of modern computer technology, network toxicology has been widely used in the related fields of traditional Chinese medicine, especially in the prediction of the toxicity of traditional Chinese medicine, which plays an important role. With the modernization of traditional Chinese medicine, people are more deeply aware of the toxicity of traditional Chinese medicine, and it is urgent to predict and evaluate the toxicity of traditional Chinese medicine with modern techniques. The study of this paper provides a reference for further understanding and development of network toxicology and its application in predicting the toxicity of Chinese medicine.
[中圖分類號]
[基金項目]